Genomic variant annotations and functional effect prediction toolbox.
Professional verison of SnpEff & SnpSift suites.
ClinEff is considered more stable thus suitable for Clinical and Production operations, whereas SnpEff/SnpSfit is designed for Research and Academic usage.
Features:
Genetic variant annotation and functional effect prediction toolbox. It annotates and predicts the effects of genetic variants on genes and proteins (such as amino acid changes).
Features:
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SnpSift annotates genomic variants using databases, filters, and manipulates genomic annotated variants. Once you annotated your files using SnpEff, you can use SnpSift to help you filter large genomic datasets in order to find the most significant variants for your experiment.
Features:
If you are using SnpEff or SnpSift in an research or academic environment, please cite our papers.
Users of SnpEff include most major research an academic institutions, as well as pharmaceutical companies and clinical sequencing projects.
SnpEff is integrated with other tools commonly used in sequencing data analysis pipelines. Most notably Galaxy, GATK and GKNO projects support SnpEff.