SnpSift TsTv
Calculate transition vs transversion ratios for each sample.
Usage example:
$ java -jar SnpSift.jar tstv hom s.vcf
Sample : 1 2 3 4 5 6 7 8 9 10 11 12 Total
Transitions : 150488 150464 158752 156674 152936 160356 152276 155314 156484 149276 151182 153468 1847670
Transversions : 70878 70358 73688 72434 70828 76150 72030 71958 72960 69348 70180 71688 862500
Ts/Tv : 2.123 2.139 2.154 2.163 2.159 2.106 2.114 2.158 2.145 2.153 2.154 2.141 2.142